Molecular Cell Biology Lodish 7th Edition Solutions Manual

This is completed downloadable of Molecular Cell Biology Lodish 7th Edition Solutions Manual

Product Details:

• ISBN-10 ‏ : ‎ 142923413X
• ISBN-13 ‏ : ‎ 978-1429234139
• Author:   Harvey Lodish (Author), Arnold Berk (Author), Chris A. Kaiser (Author), Monty Krieger (Author), Anthony Bretscher (Author), Hidde Ploegh (Author), Angelika Amon (Author), Matthew P. Scott (Author)

Molecular Cell Biology presents the key concepts in cell biology and their experimental underpinnings. The authors, all world-class researchers and teachers, incorporate medically relevant examples where appropriate to help illustrate the connections between cell biology and health and human disease. As always, a hallmark of MCB is the use of experiments to engage students in the history of cell biology and the research that has contributed to the field.

 

Table of Content:

Chapter 1 Molecules, Cells, and Evolution

1.1 The Molecules of Life

1.2 Genomes, Cell Architecture, and Cell Function

1.3 Cells into Tissues–Unicellular and Metazoan Organisms

Used for Molecular Cell Biology Investigations Chapter 2 Chemical Foundations

2.1 Covalent Bonds and Noncovalent Interactions

2.2 Chemical Building Blocks of Cells

2.3 Chemical Reactions and Equilibrium

2.4 Biochemical Energetics Chapter 3 Protein Structure and Function

3.1 Hierarchical Structure of Proteins

3.2 Protein Folding

3.3 Protein Binding and Enzyme Catalysis

3.4 Regulating Protein Function

3.5 Purifying, Detecting, and Characterizing Proteins

3.6 Proteomics Chapter 4 Basic Molecular Genetic Mechanisms

4.1 Structure of Nucleic Acids

4.2 Transcription of Protein-Coding Genes and Formation of

Functional mRNA

4.3 The Decoding of mRNA by tRNAs

4.4 Stepwise Synthesis of Proteins on Ribosomes

4.5 DNA Replication

4.6 DNA Repair and Recombination

4.7 Viruses: Parasites of the Cellular Genetic System Chapter 5 Molecular Genetic Techniques

5.1 Genetic Analysis of Mutations to Identify and Study Genes

5.2 DNA Cloning and Characterization

5.3 Using Cloned DNA Fragments to Study Gene Expression

5.4 Locating and Identifying Human Disease Genes

5.5 Inactivating the Function of Specific Genes in Eukaryotes Chapter 6 Genes, Genomics, and Chromosomes

6.1 Eukaryotic Gene Structure

6.2 Chromosomal Organization of Genes and Noncoding DNA

6.3 Transposable (Mobile) DNA Elements

6.4 Organelle DNAs

6.5 Genomics: Genome-wide Analysis of Gene Structure and Expression

6.6 Structural Organization of Eukaryotic Chromosomes

6.7 Morphology and Functional Elements of Eukaryotic Chromosomes Chapter 7 Transcriptional Control of Gene Expression

7.1 Control of Gene Expression in Bacteria

7.2 Overview of Eukaryotic Gene Control

7.3 RNA Polymerase II and the General Transcription Factors Required for Initiation

7.4 Regulatory Sequences in Protein-Coding Genes and the Proteins Through Which They Function

7.5 Molecular Mechanisms of Transcription Repression and Activation

7.6 Regulation of Transcription-Factor Activity

7.7 Epigenetic Regulation of Transcription

7.8 Other Eukaryotic Transcription Systems Chapter 8 Post-Transcriptional Gene Control

8.1 Processing of Eukaryotic Pre-mRNA

8.2 Regulation of Pre-mRNA Processing

8.3 Transport of mRNA Across the Nuclear Envelope

8.4 Cytoplasmic Mechanisms of Post-transcriptional Control

8.5 Processing of rRNA and tRNA Chapter 9 Culturing, Visualizing, and Perturbing Cells

9.1 Growing Cells in Culture

9.2 Light Microscopy: Exploring Cell Structure and Visualizing

Proteins within Cells

9.3 Electron Microscopy: High-Resolution Imaging

9.4 Isolation and Characterization of Cell Organelles

9.5 Perturbing Specific Cell Functions Chapter 10 Biomembrane Structure

10.1 The Phospholipid Bilayer: Composition and Structural

Organization

10.2 Membrane Proteins: Structure and Basic Functions

10.3 Phospholipids, Sphingolipids, and Cholesterol: Synthesis and Intracellular Movements Chapter 11 Transmembrane Transport of Ions and Small Molecules

11.1 Overview of Transmembrane Transport

11.2 Facilitated Transport of Glucose and Water

11.3 ATP-Powered Pumps and the Intracellular Ionic Environment

11.4 Nongated Ion Channels and the Resting Membrane Potential

11.5 Cotransport by Symporters and Antiporters

11.6 Transcellular Transport Chapter 12 Cellular Energetics

12.1 First Step of Harvesting Energy from Glucose: Glycolysis

12.2 Mitochondria and the Citric Acid Cycle

12.3 The Electron Transport Chain and Generation of the

Proton-Motive Force

12.4 Harnessing the Proton-Motive Force to Synthesize ATP

12.5 Photosynthesis and Light-Absorbing Pigments

12.6 Molecular Analysis of Photosystems

12.7 CO2 Metabolism During Photosynthesis Chapter 13 Moving Proteins Into Membranes and Organelles

13.1 Targeting Proteins to and Across the ER Membrane

13.2 Insertion of Membrane Proteins into the ER

13.3 Protein Modifications, Folding, and Quality Control in the ER

13.4 Targeting of Proteins to Mitochondria and Chloroplasts

13.5 Targeting of Peroxisomal Proteins

13.6 Transport into and out of the Nucleus Chapter 14 Vesicular Traffic, Secretion, and Endocytosis

14.1 Techniques for Studying the Secretory Pathway

14.2 Molecular Mechanisms of Vesicular Budding and Fusion

14.3 Early Stages of the Secretory Pathway

14.4 Later Stages of the Secretory Pathway

14.5 Receptor-Mediated Endocytosis

14.6 Directing Membrane Proteins and Cytosolic Materials to the Lysosome Chapter 15 Signal Transduction and G Protein–Coupled Receptors

15.1 Signal Transduction: From Extracellular Signal to Cellular Response

15.2 Studying Cell-Surface Receptors and Signal Transduction Proteins

15.3 G Protein–Coupled Receptors: Structure and Mechanism

15.4 G Protein–Coupled Receptors That Regulate Ion Channels

15.5 G Protein–Coupled Receptors That Activate or Inhibit Adenylyl Cyclase

15.6 G Protein–Coupled Receptors That Trigger Elevations in Cytosolic Ca2+ Chapter 16 Signaling Pathways That Control Gene Expression

16.1 Receptors That Activate Protein Tyrosine Kinases

16.2 The Ras/MAP Kinase Pathway

16.3 Phosphoinositide Signaling Pathways

16.4 Receptor Serine Kinases That Activate Smads

16.5 Signaling Pathways Controlled by Ubiquitination:

Wnt, Hedgehog, and NF-kB

16.6 Signaling Pathways Controlled by Protein Cleavage:

Notch/Delta, SREBP

16.7 Integration of Cellular Responses to Multiple Signaling Pathways Chapter 17 Cell Organization and Movement I:

Microfilaments

17.1 Microfilaments and Actin Structures

17.2 Dynamics of Actin Filaments

17.3 Mechanisms of Actin Filament Assembly

17.4 Organization of Actin-Based Cellular Structures

17.5 Myosins: Actin-Based Motor Proteins

17.6 Myosin-Powered Movements

17.7 Cell Migration: Mechanism, Signaling and Chemotaxis Chapter 18 Cell Organization and Movement II:

Microtubules and Intermediate Filaments

18.1 Microtubule Structure and Organization

18.2 Microtubule Dynamics

18.3 Regulation of Microtubule Structure and Dynamics

18.4 Kinesins and Dyneins: Microtubule-Based Motor Proteins

18.5 Cilia and Flagella: Microtubule-Based Surface Structures

18.6 Mitosis

18.7 Intermediate Filaments

18.8 Coordination and Cooperation between Cytoskeletal Elements Chapter 19 The Eukaryotic Cell Cycle

19.1 Overview of the Cell Cycle and its Control

19.2 Model Organisms and Methods to Study the Cell Cycle

19.3 Regulation of CDK Activity

19.4 Commitment to the Cell Cycle and DNA Replication

19.5 Entry into Mitosis

19.6 Completion of Mitosis: Chromosome Segregation and Exit from Mitosis

19.7 Surveillance Mechanisms in Cell Cycle Regulation

19.8 Meiosis: A Special Type of Cell Division Chapter 20 Integrating Cells Into Tissues

20.1 Cell-Cell and Cell-Matrix Adhesion: An Overview

20.2 Cell-Cell and Cell-ECM Junctions and Their Adhesion Molecules

20.3 The Extracellular Matrix I: The Basal Lamina

20.4 The Extracellular Matrix II: Connective Tissue

20.5 Adhesive Interactions in Motile and Nonmotile Cells

20.6 Plant Tissues Chapter 21 Stem Cells, Cell Asymmetry, and Cell Death

21.1 Early Metazoan Development and Embryonic Stem Cells

21.2 Stem Cells and Niches in Multicellular Organisms

21.3 Regulation of Asymmetric Cell Division

21.4 Cell Death and Its Regulation Chapter 22 Nerve Cells

22.1 Neurons and Glia: Building Blocks of the Nervous System

22.2 Voltage-Gated Ion Channels and the Propagation of Action Potentials

22.3 Communication at Synapses

22.4 Sensing the Environment: Touch, Pain, Taste, and Smell Chapter 23 Immunology

23.1 Overview of Host Defenses

23.2 Immunoglobulins: Structure and Function

23.3 Generation of Antibody Diversity and B-Cell Development

23.4 The MHC and Antigen Presentation

23.5 T Cells, T-Cell Receptors, and T-Cell Development

23.6 Collaboration of Immune-System Cells in the Adaptive ResponseChapter 24 Cancer

24.1 Tumor Cells and the Onset of Cancer

24.2 The Genetic Basis of Cancer

24.3 Cancer and the Misregulation of Growth Regulatory Pathways

24.4 Cancer and Mutation of Cell Division and Checkpoint Regulators

24.5 Carcinogens and Caretaker Genes in Cancer

 

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