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ISBN-10 ‏ : ‎ 0323512275
ISBN-13 ‏ : ‎ 978-0323512275
Author: Jacqueline Burchum

With a clear explanation of drug prototypes and how they work, Lehne’s Pharmacology for Nursing Care, 10th Edition gives you the background you need to understand drugs currently on the market, and those not yet released. This perennial favorite of students and teachers simplifies complex concepts while distinguishing need-to-know content from the material that’s merely nice to know. The 10^th edition includes updated drug content to reflect the very latest FDA approvals, withdrawals, and therapeutic uses, as well as corresponding updated nursing content. It also includes an updated prototype drugs section, summarizing their major uses, and an updated table detailing care throughout the lifespan of the patient. Additionally, each chapter ends with a nursing implications summary to help you fully understand the material and apply it to clinical nursing practice.

Prototype Drugs features serve as a quick-reference learning aid so you can apply your understanding to related drugs currently on the market as well as drugs that will be released in the future.
UNIQUE! Engaging writing style with clear explanations makes difficult pharmacology concepts easy to grasp and even enjoyable to learn.
Nursing implications of drug therapy are integrated throughout the text to reinforce the integral relationship between drug therapy and nursing care.
UPDATED Special Interest Topic boxes focus on currently trending issues in pharmacology, eliminating out-of-date content.
Large print highlights essential, need-to-know information, and small print indicates nice-to-know information.
QSEN focus includes Patient-Centered Care Across the Life Span featureshighlighting safe and appropriate patient care during different phases of life.
Safety Alert features emphasize the QSEN competency relating to patient safety.
Student-friendly features make learning easier with concise drug summary tables, chapter outlines, key points, and a visual guide to the prototype drugs in each class.
Concise drug summary tables present detailed information for individual drugs, including drug class, generic and trade names, dosages, routes, and indications.
Selected Canadian drug names are indicated with a maple-leaf icon throughout the text.
Separate Bioterrorism chapter discusses the clinical manifestations and treatment of biological weapon attacks.

NEW! Thoroughly updated drug content reflects the very latest FDA drug approvals, withdrawals, and therapeutic uses, as well as corresponding updated nursing content
NEW! Additional images included to accompany difficult concepts.
NEW! Inclusion of more student practice questions provide additional help for learning the material.

Table of Content:

Chapter 1 Orientation to Pharmacology
Four Basic Terms
Properties of an Ideal Drug
The Therapeutic Objective
Factors That Determine the Intensity of Drug Responses
Key Points
Chapter 2 Application of Pharmacology in Nursing Practice
Evolution of Nursing Responsibilities Regarding Drugs
Application of Pharmacology in Patient Care
Application of Pharmacology in Patient Education
Application of the Nursing Process in Drug Therapy
Key Points
Chapter 3 Drug Regulation, Development, Names, and Information
Landmark Drug Legislation
Hazardous Drug Exposure
New Drug Development
Drug Names
Over-the-Counter Drugs
Sources of Drug Information
Key Points
Unit II Basic Principles of Pharmacology
Chapter 4 Pharmacokinetics
Application of Pharmacokinetics in Therapeutics
A Note to Chemophobes
Passage of Drugs Across Membranes
Absorption
Distribution
Metabolism
Excretion
Time Course of Drug Responses
Key Points
Chapter 5 Pharmacodynamics
Dose-Response Relationships
Drug-Receptor Interactions
Drug Responses That Do Not Involve Receptors
Interpatient Variability in Drug Responses
The Therapeutic Index
Key Points
Chapter 6 Drug Interactions
Drug-Drug Interactions
Drug-Food Interactions
Drug-Supplement Interactions
Key Points
Chapter 7 Adverse Drug Reactions and Medication Errors
Adverse Drug Reactions
Medication Errors
Key Points
Chapter 8 Individual Variation in Drug Responses
Body Weight and Composition
Age
Pathophysiology
Tolerance
Placebo Effect
Variability in Absorption
Genetics and Pharmacogenomics
Gender- and Race-Related Variations
Comorbidities and Drug Interactions
Diet
Failure to Take Medicine as Prescribed
Key Points
Unit III Drug Therapy Across The Life Span
Chapter 9 Drug Therapy During Pregnancy and Breast-Feeding
Drug Therapy During Pregnancy: Basic Considerations
Drug Therapy During Pregnancy: Teratogenesis
Drug Therapy During Breast-Feeding
Key Points
Chapter 10 Drug Therapy in Pediatric Patients
Pharmacokinetics: Neonates and Infants
Pharmacokinetics: Children 1 Year and Older
Adverse Drug Reactions
Dosage Determination
Promoting Adherence
Key Points
Chapter 11 Drug Therapy in Older Adults
Pharmacokinetic Changes in Older Adults
Pharmacodynamic Changes in Older Adults
Adverse Drug Reactions and Drug Interactions
Promoting Adherence
Considerations for End-of-Life Care
Key Points
Unit IV Peripheral Nervous System Drugs
Section 1 Introduction
Chapter 12 Basic Principles of Neuropharmacology
How Neurons Regulate Physiologic Processes
Basic Mechanisms by Which Neuropharmacologic Agents Act
Multiple Receptor Types and Selectivity of Drug Action
An Approach to Learning About Peripheral Nervous System Drugs
Key Points
Chapter 13 Physiology of the Peripheral Nervous System
Divisions of the Nervous System
Overview of Autonomic Nervous System Functions
Basic Mechanisms By Which the Autonomic Nervous System Regulates Physiologic Processes
Anatomic Considerations
Introduction to Transmitters of the Peripheral Nervous System
Introduction to Receptors of the Peripheral Nervous System
Exploring the Concept of Receptor Subtypes
Locations of Receptor Subtypes
Functions of Cholinergic and Adrenergic Receptor Subtypes
Transmitter Life Cycles
Key Points
Section 2 Cholinergic Drugs
Chapter 14 Muscarinic Agonists and Antagonists
Introduction to Cholinergic Drugs
Muscarinic Agonists and Antagonists
Summary of Major Nursing Implications
Chapter 15 Cholinesterase Inhibitors and Their Use in Myasthenia Gravis
Reversible Cholinesterase Inhibitors
Irreversible Cholinesterase Inhibitors
Myasthenia Gravis
Key Points
Summary of Major Nursing Implications
Chapter 16 Drugs That Block Nicotinic Cholinergic Transmission
Control of Muscle Contraction
Competitive (Nondepolarizing) Neuromuscular Blockers
Depolarizing Neuromuscular Blockers: Succinylcholine
Therapeutic Uses of Neuromuscular Blockers
Key Points
Summary of Major Nursing Implications
Section 3 Adrenergic Drugs
Chapter 17 Adrenergic Agonists
Mechanisms of Adrenergic Receptor Activation
Overview of the Adrenergic Agonists
Therapeutic Applications and Adverse Effects of Adrenergic Receptor Activation
Properties of Representative Adrenergic Agonists
Key Points
Summary of Major Nursing Implications
Chapter 18 Adrenergic Antagonists
Alpha-Adrenergic Antagonists
Beta-Adrenergic Antagonists
Summary of Major Nursing Implications
Chapter 19 Indirect-Acting Antiadrenergic Agents
Centrally Acting Alpha2 Agonists
Adrenergic Neuron-Blocking Agents
Key Points
Summary of Major Nursing Implications
Unit V Central Nervous System Drugs
Section 4 Introduction
Chapter 20 Introduction to Central Nervous System Pharmacology
Transmitters of the CNS
The Blood-Brain Barrier
How Do CNS Drugs Produce Therapeutic Effects?
Adaptation of the CNS to Prolonged Drug Exposure
Development of New Psychotherapeutic Drugs
Approaching the Study of CNS Drugs
Key Points
Section 5 Drugs for Neurodegenerative Disorders
Chapter 21 Drugs for Parkinson Disease
Pathophysiology That Underlies Motor Symptoms
Overview of Motor Symptom Management
Pharmacology of Drugs Used for Motor Symptoms
Nonmotor Symptoms and Their Management
Key Points
Summary of Major Nursing Implications
Chapter 22 Drugs for Alzheimer’s Disease
Pathophysiology
Risk Factors and Symptoms
Drugs for Cognitive Impairment
Drugs for Neuropsychiatric Symptoms
Can We Prevent Alzheimer’s Disease or Delay Cognitive Decline?
Key Points
Chapter 23 Drugs for Multiple Sclerosis
Overview of MS and Its Treatment
Disease-Modifying Drugs I: Immunomodulators
Disease-Modifying Drugs II: Immunosuppressants
Drugs Used to Manage MS Symptoms
Key Points
Summary of Major Nursing Implications
Section 6 Neurologic Drugs
Chapter 24 Drugs for Seizure Disorders
Seizure Generation
Types of Seizures
How Antiepileptic Drugs Work
Basic Therapeutic Considerations
Classification of Antiepileptic Drugs
Traditional Antiepileptic Drugs
Newer Antiepileptic Drugs
Management of Generalized Convulsive Status Epilepticus
Key Points
Summary of Major Nursing Implications
Chapter 25 Drugs for Muscle Spasm and Spasticity
Drugs for Spasticity
Drugs for Localized Muscle Spasm
Other Centrally Acting Muscle Relaxants
Key Points
Summary of Major Nursing Implications
Section 7 Drugs for Pain
Chapter 26 Local Anesthetics
Basic Pharmacology of Local Anesthetics
Properties of Individual Local Anesthetics
Clinical Use of Local Anesthetics
Key Points
Summary of Major Nursing Implications
Chapter 27 General Anesthetics
Inhalation Anesthetics
Intravenous Anesthetics
Summary of Major Nursing Implications
Chapter 28 Opioid Analgesics, Opioid Antagonists, and Nonopioid Centrally Acting Analgesics
Opioid Analgesics
Opioid Antagonists
Nonopioid Centrally Acting Analgesics
Summary of Major Nursing Implications
Chapter 29 Pain Management in Patients With Cancer
Pathophysiology of Pain
Management Strategy
Assessment and Ongoing Evaluation
Drug Therapy
Nondrug Therapy
Pain Management in Special Populations
Patient Education
The Joint Commission Pain Management Standards
Key Points
Chapter 30 Drugs for Headache
Migraine Headache
Cluster Headaches
Tension-Type Headache
Summary of Major Nursing Implications
Section 8 Psychotherapeutic Drugs
Chapter 31 Antipsychotic Agents and Their Use in Schizophrenia
Schizophrenia: Clinical Presentation and Etiology
First-Generation (Conventional) Antipsychotics
Second-Generation (Atypical) Antipsychotics
Depot Antipsychotic Preparations
Management of Schizophrenia
Key Points
Summary of Major Nursing Implications
Chapter 32 Antidepressants
Major Depression: Clinical Features, Pathogenesis, and Treatment Overview
Drugs Used for Depression
Somatic (Nondrug) Therapies for Depression
Summary of Major Nursing Implications
Chapter 33 Drugs for Bipolar Disorder
Characteristics of Bipolar Disorder
Treatment of Bipolar Disorder
Mood-Stabilizing Drugs
Antipsychotic Drugs
Key Points
Summary of Major Nursing Implications
Chapter 34 Sedative-Hypnotic Drugs
Benzodiazepines
Benzodiazepine-Like Drugs
Ramelteon: A Melatonin Agonist
Suvorexant: An Orexin Antagonist
Barbiturates
Management of Insomnia
Key Points
Summary of Major Nursing Implications
Chapter 35 Management of Anxiety Disorders
Generalized Anxiety Disorder
Panic Disorder
Obsessive-Compulsive Disorder
Social Anxiety Disorder (Social Phobia)
Post-Traumatic Stress Disorder
Key Points
Chapter 36 Central Nervous System Stimulants and Attention-Deficit/Hyperactivity Disorder
Central Nervous System Stimulants
Attention-Deficit/Hyperactivity Disorder
Summary of Major Nursing Implications
Section 9 Drug Abuse
Chapter 37 Substance Use Disorders I
Definitions
Diagnostic Criteria Regarding Substance Use Disorder
Factors That Contribute to Substance Use Disorder
Neurobiology of Substance Use Disorder
Principles of Substance Use Disorder Treatment
The Controlled Substances Act
Key Points
Chapter 38 Substance Use Disorders II
Basic Pharmacology of Alcohol
Alcohol Use Disorder (AUD)
Drugs for Alcohol Use Disorder
Key Points
Summary of Major Nursing Implications
Chapter 39 Substance Use Disorders III
Basic Pharmacology of Nicotine
Pharmacologic Aids to Smoking Cessation
Key Points
Chapter 40 Substance Use Disorders IV
Heroin, Oxycodone, and Other Opioids
General CNS Depressants
Psychostimulants
Marijuana and Related Preparations
Psychedelics
Dissociative Drugs
Dextromethorphan
3,4-Methylenedioxymethamphetamine (MDMA, Ecstasy)
Inhalants
Anabolic Steroids
Key Points
Unit VI Drugs That Affect Fluid and Electrolyte Balance
Chapter 41 Diuretics
Review of Renal Anatomy and Physiology
Introduction to Diuretics
Loop Diuretics
Thiazides and Related Diuretics
Potassium-Sparing Diuretics
Mannitol: an Osmotic Diuretic
Key Points
Summary of Major Nursing Implications
Chapter 42 Agents Affecting the Volume and Ion Content of Body Fluids
Disorders of Fluid Volume and Osmolality
Acid-Base Disturbances
Potassium Imbalances
Magnesium Imbalances
Key Points
Unit VII Drugs That Affect the Heart, Blood Vessels, and Blood
Chapter 43 Review of Hemodynamics
Overview of the Circulatory System
Regulation of Cardiac Output
Regulation of Arterial Pressure
Key Points
Chapter 44 Drugs Acting on the Renin-Angiotensin-Aldosterone System
Physiology of the Renin-Angiotensin-Aldosterone System
Angiotensin-Converting Enzyme Inhibitors
Angiotensin II Receptor Blockers
Aliskiren, a Direct Renin Inhibitor
Aldosterone Antagonists
Key Points
Summary of Major Nursing Implications
Chapter 45 Calcium Channel Blockers
Calcium Channels: Physiologic Functions and Consequences of Blockade
Calcium Channel Blockers: Classification and Sites of Action
Verapamil and Diltiazem: Agents That Act on Vascular Smooth Muscle and the Heart
Dihydropyridines: Agents That Act Mainly on Vascular Smooth Muscle
Key Points
Summary of Major Nursing Implications
Chapter 46 Vasodilators
Basic Concepts in Vasodilator Pharmacology
Pharmacology of Individual Vasodilators
Key Points
Chapter 47 Drugs for Hypertension
Basic Considerations in Hypertension
Management of Chronic Hypertension
Drugs for Hypertensive Emergencies
Drugs for Hypertensive Disorders of Pregnancy
Summary of Major Nursing Implications
Chapter 48 Drugs for Heart Failure
Pathophysiology of Heart Failure
Overview of Drugs Used to Treat Heart Failure
Digoxin, a Cardiac Glycoside
Management of Heart Failure
Key Points
Summary of Major Nursing Implications
Chapter 49 Antidysrhythmic Drugs
Cardiac Electrophysiology, Dysrhythmias, and the Antidysrhythmic Drugs
Pharmacology of the Antidysrhythmic Drugs
Summary of Major Nursing Implications
Chapter 50 Prophylaxis of Atherosclerotic Cardiovascular Disease
Cholesterol
Plasma Lipoproteins
Role of LDL Cholesterol in Atherosclerosis
2013 ACC/AHA Guidelines on the Treatment of Blood Cholesterol to Reduce Atherosclerotic Cardiovascular Risk
Drugs and Other Products Used to Improve Plasma Lipid Levels
Key Points
Summary of Major Nursing Implications
Chapter 51 Drugs for Angina Pectoris
Determinants of Cardiac Oxygen Demand and Oxygen Supply
Angina Pectoris: Pathophysiology and Treatment Strategy
Organic Nitrates
Beta Blockers
Calcium Channel Blockers
Ranolazine
Treatment Measures
Key Points
Summary of Major Nursing Implications
Chapter 52 Anticoagulant, Antiplatelet, and Thrombolytic Drugs
Coagulation: Physiology and Pathophysiology
Overview of Drugs for Thromboembolic Disorders
Summary of Major Nursing Implications
Chapter 53 Management of ST-Elevation Myocardial Infarction
Pathophysiology of STEMI
Diagnosis of STEMI
Management of STEMI
Complications of STEMI
Secondary Prevention of STEMI
Key Points
Chapter 54 Drugs for Hemophilia
Basic Considerations
Preparations Used to Treat Hemophilia
Key Points
Summary of Major Nursing Implications
Chapter 55 Drugs for Deficiency Anemias
Red Blood Cell Development
Iron Deficiency
Vitamin B12 Deficiency
Folic Acid Deficiency
Summary of Major Nursing Implications
Chapter 56 Hematopoietic Agents
Hematopoietic Growth Factors
Drugs That Mimic Hematopoietic Growth Factors or Enhance Their Actions
Summary of Major Nursing Implications
Unit VIII Drugs for Endocrine Disorders
Chapter 57 Drugs for Diabetes Mellitus
Diabetes Mellitus
Insulin
Non-Insulin Medications for the Treatment of Diabetes
Acute Complications of Poor Glycemic Control
Glucagon for Treatment of Severe Hypoglycemia
Summary of Major Nursing Implications
Chapter 58 Drugs for Thyroid Disorders
Thyroid Physiology
Thyroid Function Tests
Thyroid Pathophysiology
Thyroid Hormone Preparations for Hypothyroidism
Drugs for Hyperthyroidism
Key Points
Summary of Major Nursing Implications
Chapter 59 Drugs Related to Hypothalamic and Pituitary Function
Overview of Hypothalamic and Pituitary Endocrinology
Growth Hormone
Mecasermin (Insulin-Like Growth Factor-1)
Prolactin
Antidiuretic Hormone (Vasopressin)
Antidiuretic Hormone (Vasopressin) Antagonists
Drugs for Acromegaly
Key Points
Summary of Major Nursing Implications
Chapter 60 Drugs for Disorders of the Adrenal Cortex
Physiology of the Adrenocortical Hormones
Pathophysiology of the Adrenocortical Hormones
Agents for Replacement Therapy in Adrenocortical Insufficiency
Agents for Diagnosing Adrenocortical Disorders
Key Points
Summary of Major Nursing Implications
Unit IX Women’s Health
Chapter 61 Estrogens and Progestins
The Menstrual Cycle
Estrogens
Selective Estrogen Receptor Modulators (SERMs)
Progestins
Menopausal Hormone Therapy
Key Points
Summary of Major Nursing Implications
Chapter 62 Birth Control
Effectiveness of Birth Control Methods
Selecting a Birth Control Method
Oral Contraceptives
Combination Contraceptives With Novel Delivery Systems
Long-Acting Contraceptives
Spermicides
Barrier Devices
Drugs for Medical Abortion
Key Points
Summary of Major Nursing Implications
Chapter 63 Drug Therapy for Infertility
Infertility: Causes and Treatment Strategies
Drugs Used to Treat Female Infertility
Key Points
Summary of Major Nursing Implications
Chapter 64 Drugs That Affect Uterine Function
Drugs for Preterm Labor
Drugs for Cervical Ripening and Induction of Labor
Drugs for Postpartum Hemorrhage
Drugs for Menorrhagia
Summary of Major Nursing Implications
Unit X Men’s Health
Chapter 65 Androgens
Testosterone
Clinical Pharmacology of the Androgens
Androgen Preparations for Male Hypogonadism
Androgen (Anabolic Steroid) Abuse by Athletes
Key Points
Summary of Major Nursing Implications
Chapter 66 Drugs for Erectile Dysfunction and Benign Prostatic Hyperplasia
Erectile Dysfunction
Benign Prostatic Hyperplasia
Summary of Major Nursing Implications
Unit XI Anti-Inflammatory, Antiallergic, and Immunologic Drugs
Chapter 67 Review of the Immune System
Introduction to the Immune System
Antibody-Mediated (Humoral) Immunity
Cell-Mediated Immunity
Key Points
Chapter 68 Childhood Immunization
General Considerations
Target Diseases
Specific Vaccines and Toxoids
Key Points
Chapter 69 Immunosuppressants
Calcineurin Inhibitors
mTOR Inhibitors
Glucocorticoids
Cytotoxic Drugs
Antibodies
Key Points
Summary of Major Nursing Implications
Chapter 70 Antihistamines
Histamine
The Two Types of Antihistamines: H1 Antagonists and H2 Antagonists
Histamine1 Antagonists I: Basic Pharmacology
Histamine1 Antagonists Ii: Preparations
Key Points
Summary of Major Nursing Implications
Chapter 71 Cyclooxygenase Inhibitors
Mechanism of Action
Classification of Cyclooxygenase Inhibitors
First-Generation NSAIDs
Second-Generation NSAIDs (COX-2 Inhibitors, Coxibs)
Acetaminophen
AHA Statement on the use of COX Inhibitors for Chronic Pain
Key Points
Summary of Major Nursing Implications
Chapter 72 Glucocorticoids in Nonendocrine Disorders
Review of Glucocorticoid Physiology
Pharmacology of the Glucocorticoids
Key Points
Summary of Major Nursing Implications
Unit XII Drugs for Bone and Joint Disorders
Chapter 73 Drug Therapy for Rheumatoid Arthritis
Pathophysiology of Rheumatoid Arthritis
Overview of Therapy
Nonsteroidal Anti-Inflammatory Drugs
Glucocorticoids
Nonbiologic (Traditional) Disease-Modifying Antirheumatic Drugs
Biologic Disease-Modifying Antirheumatic Drugs
Key Points
Summary of Major Nursing Implications
Chapter 74 Drug Therapy for Gout
Pathophysiology of Gout
Overview of Drug Therapy
Drugs for Acute Gouty Arthritis
Drugs for Hyperuricemia (Urate-Lowering Therapy)
Key Points
Chapter 75 Drugs Affecting Calcium Levels and Bone Mineralization
Calcium Physiology
Calcium-Related Pathophysiology
Drugs for Disorders Involving Calcium and Bone Mineralization
Osteoporosis
Key Points
Summary of Major Nursing Implications
Unit XIII Respiratory Tract Drugs
Chapter 76 Drugs for Asthma and Chronic Obstructive Pulmonary Disease
Basic Considerations
Anti-Inflammatory Drugs
Bronchodilators
Glucocorticoid–Long-Acting Beta2-Agonist Combinations
Beta2-Adrenergic Agonist–Anticholinergic Combinations
Management of Asthma
Management of COPD
Summary of Major Nursing Implications
Chapter 77 Drugs for Allergic Rhinitis, Cough, and Colds
Drugs for Allergic Rhinitis
Drugs for Cough
Cold Remedies: Combination Preparations
Key Points
Unit XIV Gastrointestinal Drugs
Chapter 78 Drugs for Peptic Ulcer Disease
Pathogenesis of Peptic Ulcers
Overview of Treatment
Antibacterial Drugs
Histamine2 Receptor Antagonists
Proton Pump Inhibitors
Other Antiulcer Drugs
Key Points
Summary of Major Nursing Implications
Chapter 79 Laxatives
General Considerations
Basic Pharmacology of Laxatives
Laxative Abuse
Key Points
Summary of Major Nursing Implications
Chapter 80 Other Gastrointestinal Drugs
Antiemetics
Drugs for Motion Sickness
Antidiarrheal Agents
Drugs for Irritable Bowel Syndrome
Drugs for Inflammatory Bowel Disease
Prokinetic Agents
Palifermin
Pancreatic Enzymes
Drugs Used to Dissolve Gallstones
Anorectal Preparations
Key Points
Unit XV Nutrition
Chapter 81 Vitamins
Basic Considerations
Fat-Soluble Vitamins
Water-Soluble Vitamins
Key Points
Chapter 82 Drugs for Weight Loss
Assessment of Weight-Related Health Risk
Overview of Obesity Treatment
Weight-Loss Drugs
A Note Regarding Drugs for Weight Loss
Key Points
Unit XVI Chemotherapy of Infectious Diseases
Chapter 83 Basic Principles of Antimicrobial Therapy
Selective Toxicity
Classification of Antimicrobial Drugs
Acquired Resistance to Antimicrobial Drugs
Selection of Antibiotics
Host Factors That Modify Drug Choice, Route of Administration, or Dosage
Dosage and Duration of Treatment
Therapy With Antibiotic Combinations
Prophylactic Use of Antimicrobial Drugs
Misuses of Antimicrobial Drugs
Monitoring Antimicrobial Therapy
Key Points
Chapter 84 Drugs That Weaken the Bacterial Cell Wall I
Introduction to the Penicillins
Properties of Individual Penicillins
Key Points
Summary of Major Nursing Implications
Chapter 85 Drugs That Weaken the Bacterial Cell Wall II
Cephalosporins
Carbapenems
Other Inhibitors of Cell Wall Synthesis
Key Points
Summary of Major Nursing Implications
Chapter 86 Bacteriostatic Inhibitors of Protein Synthesis
Tetracyclines
Macrolides
Other Bacteriostatic Inhibitors of Protein Synthesis
Key Points
Summary of Major Nursing Implications
Chapter 87 Aminoglycosides
Basic Pharmacology of the Aminoglycosides
Properties of Individual Aminoglycosides
Key Points
Summary of Major Nursing Implications
Chapter 88 Sulfonamides and Trimethoprim
Sulfonamides
Trimethoprim
Trimethoprim/Sulfamethoxazole
Key Points
Summary of Major Nursing Implications
Chapter 89 Drug Therapy for Urinary Tract Infections
Organisms That Cause Urinary Tract Infections
Specific Urinary Tract Infections and Their Treatment
Urinary Tract Antiseptics
Key Points
Chapter 90 Antimycobacterial Agents
Drugs for Tuberculosis
Drugs for Leprosy (Hansen’s Disease)
Drugs for Mycobacterium avium Complex Infection
Summary of Major Nursing Implications
Chapter 91 Miscellaneous Antibacterial Drugs
Fluoroquinolones
Additional Antibacterial Drugs
Key Points
Summary of Major Nursing Implications
Chapter 92 Antifungal Agents
Drugs for Systemic Mycoses
Drugs for Superficial Mycoses
Key Points
Summary of Major Nursing Implications
Chapter 93 Antiviral Agents I
Drugs for Infection With Herpes Simplex Viruses and Varicella-Zoster Virus
Drugs for Cytomegalovirus Infection
Drugs for Hepatitis
Drugs for Influenza
Drugs for Respiratory Syncytial Virus Infection
Summary of Major Nursing Implications
Chapter 94 Antiviral Agents II
Pathophysiology
Classification of Antiretroviral Drugs
Drug Interactions
Nucleoside/Nucleotide Reverse Transcriptase Inhibitors
Non-Nucleoside Reverse Transcriptase Inhibitors
Protease Inhibitors
Integrase Strand Transfer Inhibitors
HIV Fusion Inhibitors
CCR5 Antagonists
Management of HIV Infection
Preventing HIV Infection With Drugs
Prophylaxis and Treatment of Opportunistic Infections
HIV Vaccines
Keeping Current
Key Points
Summary of Major Nursing Implications
Chapter 95 Drug Therapy for Sexually Transmitted Infections
Chlamydia trachomatis Infections
Gonococcal Infections
Nongonococcal Urethritis
Pelvic Inflammatory Disease
Acute Epididymitis
Syphilis
Acquired Immunodeficiency Syndrome
Bacterial Vaginosis
Trichomoniasis
Chancroid
Herpes Simplex Virus Infections
Proctitis
Venereal Warts
Making Sense of Treatment
Key Points
Chapter 96 Antiseptics and Disinfectants
General Considerations
Properties of Individual Antiseptics and Disinfectants
Hand Hygiene for Healthcare Workers
Key Points
Unit XVII Chemotherapy of Parasitic Diseases
Chapter 97 Anthelmintics
Classification of Parasitic Worms
Helminthic Infestations
Drugs of Choice for Helminthiasis
Key Points
Chapter 98 Antiprotozoal Drugs I
Life Cycle of the Malaria Parasite
Types of Malaria
Principles of Antimalarial Therapy
Pharmacology of the Major Antimalarial Drugs
Key Points
Chapter 99 Antiprotozoal Drugs II
Protozoal Infections
Drugs of Choice for Protozoal Infections
Key Points
Chapter 100 Ectoparasiticides
Ectoparasitic Infestations
Pharmacology of Ectoparasiticides
Key Points
Unit XVIII Cancer Chemotherapy
Chapter 101 Basic Principles of Cancer Chemotherapy
What Is Cancer?
The Growth Fraction and Its Relationship to Chemotherapy
Obstacles to Successful Chemotherapy
Strategies for Achieving Maximum Benefits From Chemotherapy
Major Toxicities of Chemotherapeutic Drugs
Making the Decision to Treat
Looking Ahead
Key Points
Chapter 102 Anticancer Drugs I
Introduction to the Cytotoxic Anticancer Drugs
Alkylating Agents
Platinum Compounds
Antimetabolites
Hypomethylating Agents
Antitumor Antibiotics
Mitotic Inhibitors
Topoisomerase Inhibitors
Miscellaneous Cytotoxic Drugs
Key Points
Chapter 103 Anticancer Drugs II
Drugs for Breast Cancer
Drugs for Prostate Cancer
Targeted Anticancer Drugs
Immunostimulants
Other Noncytotoxic Anticancer Drugs
Unit XIX Miscellaneous Drugs and Therapies
Chapter 104 Drugs for the Eye
Drugs for Glaucoma
Cycloplegics and Mydriatics
Drugs for Allergic Conjunctivitis
Drugs for Age-Related Macular Degeneration
Additional Ophthalmic Drugs
Key Points
Chapter 105 Drugs for the Skin
Anatomy of the Skin
Topical Drug Formulations
Topical Glucocorticoids
Keratolytic Agents
Acne
Drugs for Rosacea
Sunscreens
Psoriasis
Drugs for Actinic Keratoses
Drugs for Atopic Dermatitis (Eczema)
Agents Used to Remove Warts
Drugs for Nonsurgical Cosmetic Procedures
Antiperspirants and Deodorants
Drugs for Seborrheic Dermatitis and Dandruff
Drugs for Hair Loss
Eflornithine for Unwanted Facial Hair
Drugs for Impetigo
Local Anesthetics
Key Points
Chapter 106 Drugs for the Ear
Anatomy of the Ear
Otitis Media and Its Management
Otitis Externa and Its Management
Key Points
Summary of Major Nursing Implications
Chapter 107 Additional Noteworthy Drugs
Drugs for Pulmonary Arterial Hypertension
Drugs for Neonatal Respiratory Distress Syndrome
Drugs for Cystic Fibrosis
Drugs for Sickle Cell Anemia
Phosphate Binders for Patients on Dialysis
Gamma-Hydroxybutyrate for Cataplexy in Patients With Narcolepsy
Riluzole for Amyotrophic Lateral Sclerosis
Tetrabenazine for Chorea of Huntington’s Disease
Drugs for Fibromyalgia
Drugs for Hereditary Angioedema
Belimumab for Systemic Lupus Erythematosus
Key Points
Chapter 108 Complementary and Alternative Therapy
Regulation of Dietary Supplements
Private Quality Certification Programs
Standardization of Herbal Products
Adverse Interactions With Conventional Drugs
Some Commonly Used Dietary Supplements
Harmful Supplements to Avoid
Key Points
Unit XX Toxicology
Chapter 109 Management of Poisoning
Fundamentals of Treatment
Drugs and Procedures Used to Minimize Poison Absorption
Drugs and Procedures Used for Poison Removal
Specific Antidotes
Poison Control Centers
Key Points
Chapter 110 Potential Weapons of Biologic, Radiologic, and Chemical Terrorism
Bacteria and Viruses
Biotoxins
Chemical Weapons
Radiologic Weapons
Key Points
Appendix A Canadian Drug Information*
Canadian Drug Legislation
Drug Advertising
International System of Units
Drug Serum Concentrations
Further Reading
Appendix B Prototype Drugs and Their Major Uses
Peripheral Nervous System Drugs
Central Nervous System Drugs
Diuretics
Drugs That Affect the Heart, Blood Vessels, and Blood
Drugs for Endocrine Disorders
Women’s Health
Men’s Health
Anti-Inflammatory, Antiallergic, and Immunologic Drugs
Drugs for Bone and Joint Disorders
Respiratory Tract Drugs
Gastrointestinal Drugs
Drugs for Weight Loss
Drugs for Bacterial Infections
Drugs for Fungal Infections
Drugs for Viral Infections
Drugs for Parasitic Diseases
Anticancer Drugs: Cytoxic Agents
Anticancer Drugs: Hormonal Agents, Targeted Drugs, and Other Noncytotoxic Anticancer Drugs
Other Important Drugs
Index
Special Interest Topics

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Test Bank for Lehnes Pharmacology for Nursing Care 10th Edition By Burchum

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