This is completed downloadable of Test Bank for Pathophysiology: The Biologic Basis for Disease in Adults and Children 8th Edition
Product Details:
- ISBN-10 ‏ : ‎ 9780323583473
- ISBN-13 ‏ : ‎ 978-0275972486
- Author:Â Kathryn L. McCance
Learn the what, how, and why of pathophysiology! With easy-to-read, in-depthdescriptions of disease, disease etiology, and disease processes, Pathophysiology: The Biologic Basis for Disease in Adults and Children, 8th Edition helps you understand the most important and most complex pathophysiology concepts. This updated text includes more than 1,300 full-color illustrations and photographs to make it easier to identify normal anatomy and physiology, as well as alterations of function. This edition includes a NEW chapter on obesity and nutritional disorders, along withexpanded coverage of rare diseases and epigenetics. It’s the most comprehensive and authoritative pathophysiology text available!
- The most comprehensive and authoritative pathophysiology text on the market provides unparalleled coverage of Pathophysiology content.
- Over 1,300 full-color illustrations and photographs depict the clinical manifestations of disease and disease processes ― more than in any other pathophysiology text.
- Consistent presentation of diseases includes pathophysiology, clinical manifestations, and evaluation and treatment.
- Lifespan content includes ten separate pediatric chapters and special sections with aging and pediatrics content.
- Outstanding authors Kathryn McCance and Sue Huether have extensive backgrounds as researchers and instructors, and utilize expert contributors, consultants, and reviewers in developing this edition.
- Algorithms and flowcharts of diseases and disorders make it easy for you to follow the sequential progression of disease processes.
- Additional What’s New boxes highlight the most current research and clinical development.
- Nutrition and Disease boxes explain the link between concepts of health promotion and disease.
- Chapter summary reviews provide concise synopses of the main points of each chapter.
- NEW! Chapter on obesity and nutritional disorders thoroughly covers these growing global concerns.
- NEW! Added coverage of rare diseases and epigenetics further explore genetic disease traits.
- NEW! Over 50 new or heavily revised illustrations visually highlight pathophysiology concepts.
- NEW! More than 30 new 3D animations on Evolve bring difficult concepts to life for a new perspective on disease processes.
Table of Content:
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Cover image
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Title Page
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Table of Contents
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What’s New?
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About the Cover Image
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Copyright
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Contributors
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Reviewers
-
Preface
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Organization and Content: What’s New in the Eighth Edition
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Features to Promote Learning
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Art Program
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Ancillaries
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Acknowledgments
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Introduction to Pathophysiology
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References
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Part One Central Concepts of Pathophysiology: Cells and Tissues
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Unit I The Cell
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1 Cellular Biology
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Prokaryotes and Eukaryotes
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Cellular Functions
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Structure and Function of Cellular Components
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Cell-to-Cell Adhesions
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Cellular Communication and Signal Transduction
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Cellular Metabolism
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Membrane Transport: Cellular Intake and Output
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Cellular Reproduction: the Cell Cycle
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Tissues
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Summary Review
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Key Terms
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References
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2 Altered Cellular and Tissue Biology
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Cellular Adaptation
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Cellular Injury
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Manifestations of Cellular Injury
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Cellular Death
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Aging and Altered Cellular and Tissue Biology
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Somatic Death
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Summary Review
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Key Terms
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References
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3 The Cellular Environment
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Distribution of Body Fluids
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Aging and Distribution of Body Fluids
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Alterations in Water Movement
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Sodium, Chloride, and Water Balance
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Alterations in Sodium, Water, and Chloride Balance
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Alterations in Potassium, Calcium, Phosphate, and Magnesium Balance
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Acid-Base Balance
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Summary Review
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Key Terms
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References
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Unit II Genes, Gene-Environment Interaction, and Epigenetics
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4 Genes and Genetic Diseases
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DNA, RNA, and Proteins: Heredity at the Molecular Level
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Chromosomes
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Elements of Formal Genetics
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Transmission of Genetic Diseases
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Linkage Analysis and Gene Identification
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Summary Review
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Key Terms
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References
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5 Genes, Environment-Lifestyle, and Common Diseases
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Factors Influencing Incidence of Disease in Populations
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Principles of Multifactorial Inheritance
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Nature and Nurture: Disentangling the Effects of Genes and Environment
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Genetics of Common Diseases
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Summary Review
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Key Terms
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References
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6 Epigenetics and Disease
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Overview of Epigenetic Mechanisms
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Epigenetics and Human Development
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Genomic Imprinting
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Epigenetics in Cognitive Development and Mental Health
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Exploring the Possible Multigenerational Persistence of Epigenetic States That Arise in Response to Environmental Factors
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Epigenetic Change Over the Life Span
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Molecular and Computational Tools for Exploring Epigenetic States
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Epigenetics and Cancer
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Emerging Strategies for the Treatment of Epigenetic Disease
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Future Directions
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Summary Review
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Key Terms
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References
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Unit III Mechanisms of Self-Defense
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7 Innate Immunity
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Human Defense Mechanisms
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First Line of Defense: Physical, Mechanical, and Biochemical Barriers and Normal Microbiome
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Second Line of Defense: Inflammation
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Local Manifestations of Inflammation
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Systemic Manifestations of Acute Inflammation
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Chronic Inflammation
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Wound Healing
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Pediatrics: Innate Immunity in the Newborn Child
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Aging: Innate Immunity in the Older Adult Population
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Summary Review
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Key Terms
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References
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8 Adaptive Immunity
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General Characteristics of Adaptive Immunity
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Recognition and Response
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Generation of Clonal Diversity
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Induction of an Immune Response: Clonal Selection
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Effector Mechanisms
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Fetal and Neonatal Immune Function
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Aging and Immune Function
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Summary Review
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Key Terms
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References
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9 Alterations in Immunity and Inflammation
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Hypersensitivity: Allergy, Autoimmunity, and Alloimmunity
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References:
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Deficiencies in Immunity
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Summary Review
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Key Terms
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References
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10 Infection
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Emerging Infections
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References
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Microorganisms and Humans: a Dynamic Relationship
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Microorganisms and Infections
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References
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References
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References
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References
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Human Immunodeficiency Virus and Acquired Immunodeficiency Syndrome
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Countermeasures Against Pathogens
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References
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Summary Review
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Key Terms
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References
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11 Stress and Disease
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Historical Background and General Concepts
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Concepts of Stress, Homeostasis, and Allostasis
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Stress Response
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Stress, Illness, and Coping
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Aging and Stress: Stress-Age Syndrome
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Summary Review
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Key Terms
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References
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Unit IV Cellular Proliferation: Cancer
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12 Cancer Biology
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Cancer Characteristics and Terminology
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The Biology of Cancer Cells
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Clinical Manifestations of Cancer
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Diagnosis and Staging of Cancer
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Treatment of Cancer
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Targeted Disruption of Cancer
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Summary Review
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Key Terms
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References
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13 Cancer Epidemiology
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Genetics, Epigenetics, and Tissue
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Incidence and Mortality Trends
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In Utero and Early Life Conditions
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Environmental-Lifestyle Factors
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Chemicals and Occupational Hazards as Carcinogens
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Summary Review
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Key Terms
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References
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14 Cancer in Children
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Incidence and Types of Cancer
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Etiology
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Prognosis
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Summary Review
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Key Terms
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References
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Part Two Pathophysiologic Alterations: Organs and Systems
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Unit V Pathophysiologic Alterations: Organs and Systems
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15 Structure and Function of the Neurologic System
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Overview and Organization of the Nervous System
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Cells of the Nervous System
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Nerve Impulse
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Central Nervous System
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Peripheral Nervous System
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Autonomic Nervous System
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Aging and the Nervous System
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Tests of Nervous System Structure and Function
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Summary Review
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Key Terms
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References
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16 Pain, Temperature Regulation, Sleep, and Sensory Function
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Pain
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Pediatrics and Perception of Pain
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Aging and Perception of Pain
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Temperature Regulation
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Pediatrics and Temperature Regulation
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Aging and Temperature Regulation
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Sleep
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Pediatrics and Sleep Patterns
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Aging and Sleep Patterns
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Somatosensory Function and the Special Senses
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Aging and Vision
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Aging and Hearing
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Aging and Olfaction and Taste
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Summary Review
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Key Terms
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References
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17 Alterations in Cognitive Systems, Cerebral Hemodynamics, and Motor Function
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Alterations in Cognitive Systems
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Alterations in Cerebral Hemodynamics
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Alterations in Neuromotor Function
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Summary Review
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Key Terms
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References
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18 Disorders of the Central and Peripheral Nervous Systems and the Neuromuscular Junction
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Central Nervous System Disorders
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Peripheral Nervous System and Neuromuscular Junction Disorders
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Tumors of the Central Nervous System
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Summary Review
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Key Terms
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References
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19 Neurobiology of Schizophrenia, Mood Disorders, Anxiety Disorders, and Obsessive-Compulsive Disorder
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Schizophrenia
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Mood Disorders: Depression and Bipolar Disorder
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Anxiety Disorders
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Obsessive-Compulsive Disorder
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Summary Review
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Key Terms
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References
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20 Alterations of Neurologic Function in Children
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Development of the Nervous System in Children
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Structural Malformations
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Alterations in Function: Encephalopathies
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Cerebrovascular Disease in Children
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Epilepsy and Seizure Disorders in Children
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Childhood Tumors
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Summary Review
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Key Terms
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References
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Unit VI The Endocrine System
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21 Mechanisms of Hormonal Regulation
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Mechanisms of Hormonal Regulation
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Structure and Function of the Endocrine Glands
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Aging and the Endocrine System
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Summary Review
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Key Terms
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References
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22 Alterations of Hormonal Regulation
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Mechanisms of Hormonal Alterations
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Alterations of the Hypothalamic-Pituitary System
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Alterations of Thyroid Function
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Alterations of Parathyroid Function
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Dysfunction of the Endocrine Pancreas: Diabetes Mellitus
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Alterations of Adrenal Function
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Summary Review
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Key Terms
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References
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23 Obesity and Disorders of Nutrition
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Adipose Tissue
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Obesity
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Anorexia Nervosa, Bulimia Nervosa, and Binge Eating Disorder
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Starvation
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Anorexia of Aging
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Summary Review
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Key Terms
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References
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Unit VII The Reproductive Systems
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24 Structure and Function of the Reproductive Systems
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Development of the Reproductive Systems
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The Female Reproductive System
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Structure and Function of the Breast
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The Male Reproductive System
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Tests of Reproductive Function
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Aging and Reproductive Function
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Summary Review
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Key Terms
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References
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25 Alterations of the Female Reproductive System
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Abnormalities of Reproductive Tract Development
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Alterations of Sexual Maturation
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Disorders of the Female Reproductive System
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Disorders of the Female Breast
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Summary Review
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Key Terms
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References
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26 Alterations of the Male Reproductive System
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Alterations of Sexual Maturation
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Disorders of the Male Reproductive System
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Disorders of the Male Breast
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Summary Review
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Key Terms
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References
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27 Sexually Transmitted Infections
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Sexually Transmitted Urogenital Infections
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Sexually Transmitted Infections of Other Body Systems
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Summary Review
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Key Terms
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References
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Unit VIII The Hematologic System
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28 Structure and Function of the Hematologic System
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Components of the Hematologic System
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Development of Blood Cells
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References
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Mechanisms of Hemostasis
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Clinical Evaluation of the Hematologic System
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Pediatrics and the Hematologic System
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Aging and the Hematologic System
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Summary Review
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Key Terms
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References
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29 Alterations of Erythrocyte, Platelet, and Hemostatic Function
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Anemia
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Myeloproliferative Red Blood Cell Disorders
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Alterations of Platelets and Coagulation
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Summary Review
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Key Terms
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References
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30 Alterations of Leukocyte and Lymphoid Function
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Alterations of Leukocyte Function
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Alterations of Lymphoid Function
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Alterations of Splenic Function
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Summary Review
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Key Terms
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References
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31 Alterations of Hematologic Function in Children
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Fetal and Neonatal Hematopoiesis
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Postnatal Changes in the Blood
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Disorders of Erythrocytes
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Disorders of Coagulation and Platelets
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Neoplastic Disorders
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Summary Review
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Key Terms
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References
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Unit IX The Cardiovascular and Lymphatic Systems
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32 Structure and Function of the Cardiovascular and Lymphatic Systems
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Circulatory System
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The Heart
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The Systemic Circulation
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Lymphatic System
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Tests of Cardiovascular Function
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Aging and the Cardiovascular System
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Summary Review
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Key Terms
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References
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33 Alterations of Cardiovascular Function
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Diseases of the Veins
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Diseases of the Arteries
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Disorders of the Heart Wall
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Manifestations of Heart Disease
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Summary Review
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Key Terms
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References
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34 Alterations of Cardiovascular Function in Children
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Development of The Cardiovascular System
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Congenital Heart Defects
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Acquired Cardiovascular Disorders
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Summary Review
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Key Terms
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References
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Unit X The Pulmonary System
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35 Structure and Function of the Pulmonary System
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Structures of the Pulmonary System
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References
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Functions of the Pulmonary System
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Tests of Pulmonary Function
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Aging and the Pulmonary System
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Summary Review
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Key Terms
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References
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36 Alterations of Pulmonary Function
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Clinical Manifestations of Pulmonary Alterations
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Disorders of the Chest Wall and Pleura
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Pulmonary Disorders
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References
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Summary Review
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Key Terms
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References
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37 Alterations of Pulmonary Function in Children
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Structure and Function
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Disorders of the Upper Airways
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Disorders of the Lower Airways
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Sudden Infant Death Syndrome
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Summary Review
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Key Terms
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References
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Unit XI The Renal and Urologic Systems
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38 Structure and Function of the Renal and Urologic Systems
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Structures of the Renal System
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Renal Blood Flow
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Kidney Function
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Tests of Renal Function
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Aging and Renal Function
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Summary Review
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Key Terms
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References
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39 Alterations of Renal and Urinary Tract Function
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Urinary Tract Obstruction
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Urinary Tract Infection
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Glomerular Disorders
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Acute Kidney Injury
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Chronic Kidney Disease
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Summary Review
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Key Terms
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References
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40 Alterations of Renal and Urinary Tract Function in Children
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Structure and Function of the Urinary System in Children
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Alterations in Renal and Bladder Function in Children
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Summary Review
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Key Terms
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References
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Unit XII The Digestive System
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41 Structure and Function of the Digestive System
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The Gastrointestinal Tract
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Accessory Organs of Digestion
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Tests of Digestive Function
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Aging and the Gastrointestinal System
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Summary Review
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Key Terms
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References
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42 Alterations of Digestive Function
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Disorders of the Gastrointestinal Tract
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Disorders of the Accessory Organs of Digestion
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Cancer of the Digestive System
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Summary Review
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Key Terms
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References
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43 Alterations of Digestive Function in Children
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Disorders of the Gastrointestinal Tract
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Disorders of the Liver
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Summary Review
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Key Terms
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References
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Unit XIII The Musculoskeletal System
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44 Structure and Function of the Musculoskeletal System
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Structure and Function of Bones
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Structure and Function of Joints
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Structure and Function of Skeletal Muscles
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Tests of Musculoskeletal Function
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Aging and the Musculoskeletal System
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Summary Review
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Key Terms
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References
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45 Alterations of Musculoskeletal Function
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Musculoskeletal Injuries
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Disorders of Bones
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Disorders of Joints
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References
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Disorders of Skeletal Muscle
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Summary Review
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Key Terms
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References
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46 Alterations of Musculoskeletal Function in Children
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Musculoskeletal Development in Children
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Musculoskeletal Alterations in Children
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Nonaccidental Trauma
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Summary Review
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Key Terms
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References
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Unit XIV The Integumentary System
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47 Structure, Function, and Disorders of the Integument
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Structure and Function of the Skin
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Aging and Skin Integrity
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Disorders of the Skin
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Disorders of the Hair
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Disorders of the Nail
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Summary Review
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Key Terms
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References
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48 Alterations of the Integument in Children
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Acne Vulgaris
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Dermatitis
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Infections of the Skin
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Insect Bites and Parasites
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Cutaneous Hemangiomas and Vascular Malformations
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Other Skin Disorders
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Summary Review
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Key Terms
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References
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Unit XV Multiple Interacting Systems
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49 Shock, Multiple Organ Dysfunction Syndrome, and Burns in Adults
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Shock
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Multiple Organ Dysfunction Syndrome
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Burns
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Summary Review
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Key Terms
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References
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50 Shock, Multiple Organ Dysfunction Syndrome, and Burns in Children
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Shock and Multiple Organ Dysfunction Syndrome
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Burns
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Summary Review
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Key Terms
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References
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Glossary
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