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ISBN-10 : 0729542645
ISBN-13 : 978-0729542647
Author: Judy Craft; Christopher Gordon
Written by Judy Craft and Christopher Gordon, Understanding Pathophysiology 3e remains Australia and New Zealand’s leading pathophysiology text for nursing and allied health students. Updated to include the most current scientific and clinical case material across the life span, complex subject manner is presented in an approachable and easy-to-understand format. Beginning with essential concepts, the text examines the normal structure and function of each body system, followed by the alterations to that system caused by disease. Conditions particularly relevant to children and to the ageing are described in separate sections in each chapter to demonstrate disease processes across the life span.
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Table Of Content:
- Cover image
- Title Page
- Table of Contents
- Copyright
- About the Authors
- Australian and New Zealand Contributors
- US Contributors
- Reviewers
- Preface
- Organisation of content
- The Australian and New Zealand context
- Concept maps: a unique feature of the text
- Acknowledgments
- Text Features
- Part One Essential concepts of pathophysiology
- Introduction
- Chapter 1 Introduction to clinical science
- Introduction
- Essential pathophysiology
- Essential anatomy
- Essential physiology
- Essential chemistry
- Essential physics
- Review questions
- Chapter 2 Homeostasis
- Introduction
- Homeostasis
- Regulation of homeostasis
- Disturbances of homeostasis lead to pathophysiology
- Review questions
- Chapter 3 Cellular structure and function
- Introduction
- Cellular structure and function
- Cellular components
- The cell membrane
- Cellular receptors and communication
- Membrane transport
- Cellular metabolism
- Tissues
- Review questions
- Chapter 4 Altered cellular function
- Introduction
- Causes of cellular injury
- Mechanisms of cellular injury
- Cellular adaptation
- Reversible and irreversible cell injury
- Death
- Review questions
- Chapter 5 Genes
- Introduction
- The nucleus
- Cell proliferation
- DNA, RNA and proteins: heredity at the molecular level
- Elements of genetics
- Inheritance of traits
- Newborn screening
- Review questions
- Part Two Alterations to regulation and control
- Introduction
- Chapter 6 The structure and function of the neurological system
- Introduction
- Organisation of the nervous system
- Cells of the nervous system
- Nerve injury and regeneration
- The nerve impulse
- The central nervous system
- The peripheral nervous system
- The autonomic nervous system
- Sensory function
- Review questions
- Chapter 7 Pain
- Introduction
- The definition of pain
- Types of pain
- Pain terminology
- The physiology of pain
- Clinical manifestations of pain
- Evaluation and treatment
- Pathophysiology of pain
- Review questions
- Chapter 8 Concepts of neurological dysfunction
- Introduction
- Alterations in cerebral homeostasis
- Alterations in cognitive function
- Alterations in motor function
- Review questions
- Chapter 9 Alterations of neurological function across the life span
- Introduction
- Cerebrovascular disorders
- Trauma to the central nervous system
- Degenerative disorders of the central nervous system
- Peripheral nervous system and neuromuscular junction disorders
- Infection and inflammation of the central nervous system
- Tumours of the nervous system
- Review questions
- Chapter 10 The structure and function of the endocrine system
- Introduction
- Mechanisms of hormonal regulation
- The structure and function of the endocrine glands
- Review questions
- Chapter 11 Alterations of endocrine function across the life span
- Introduction
- Mechanisms of hormonal alterations
- Alterations of pituitary function
- Alterations of adrenal function
- Alterations of pancreatic function
- Alterations of thyroid function
- Alterations of parathyroid function
- Review questions
- Part Three Alterations to protection and movement
- Introduction
- Chapter 12 The structure and function of the immune system
- Introduction
- Human defence mechanisms
- Humoral and cell-mediated immunity
- Induction of the immune response
- Review questions
- Chapter 13 Inflammation and fever
- Introduction
- Acute inflammation
- Cellular components of inflammation
- Inflammatory mediators
- Plasma protein systems
- Chronic inflammation
- Clinical manifestations of inflammation
- Fever
- Wound healing
- Review questions
- Chapter 14 Infection
- Introduction
- Infection rates
- Definitions
- Microorganisms
- Antimicrobials
- Vaccines
- Infections
- Antimicrobial resistance
- Review questions
- Chapter 15 Alterations of immune function across the life span
- Introduction
- Hypersensitivity reactions
- Transplantation
- The ABO blood group system
- Autoimmune diseases
- Immune deficiencies
- Review questions
- Chapter 16 The structure and function of the haematological system
- Introduction
- Components of the haematological system
- The development of blood cells
- The mechanisms of haemostasis
- Review questions
- Chapter 17 Alterations of haematological function across the life span
- Introduction
- Alterations of erythrocyte function
- Alterations of platelets and coagulation
- Alterations of leucocytes
- Alterations of lymphoid function
- Review questions
- Chapter 18 The structure and function of the integumentary system
- Introduction
- The structure of the skin
- Appendages of the skin
- The function of the integumentary system
- Review questions
- Chapter 19 Alterations of the integumentary system across the life span
- Introduction
- Skin lesions
- Skin cancer
- Inflammatory disorders of the skin
- Infections of the integumentary system
- Traumatic conditions of the integumentary system
- Vascular disorders
- Review questions
- Chapter 20 The structure and function of the musculoskeletal system
- Introduction
- The structure and function of bones
- The structure and function of joints
- The structure and function of skeletal muscles
- Review questions
- Chapter 21 Alterations of musculoskeletal function across the life span
- Introduction
- Musculoskeletal injuries
- Disorders of bone and joints
- Disorders of skeletal muscle
- Integrative conditions related to the musculoskeletal system
- Review questions
- Part Four Alterations to body maintenance
- Introduction
- Chapter 22 The structure and function of the cardiovascular and lymphatic systems
- Introduction
- The circulatory system
- The structure of the heart
- Blood flow during the cardiac cycle
- The coronary circulation
- Structures that control heart function
- The electrocardiogram
- Factors affecting cardiac performance
- The physiology of cardiovascular control
- The systemic circulation
- Blood pressure and blood flow
- The lymphatic system
- Review questions
- Chapter 23 Alterations of cardiovascular function across the life span
- Introduction
- Alterations of blood flow and pressure
- Alterations of the heart wall
- Alterations of cardiac conduction
- Heart failure
- Shock
- Review questions
- Chapter 24 The structure and function of the pulmonary system
- Introduction
- The structure of the pulmonary system
- The function of the pulmonary system
- Review questions
- Chapter 25 Alterations of pulmonary function across the life span
- Introduction
- Disorders of the pulmonary system
- Infections of the pulmonary system
- Lung cancer
- Obstructive sleep apnoea
- Alterations of pulmonary blood flow and pressure
- Clinical manifestations of pulmonary alterations
- Review questions
- Chapter 26 The structure and function of the digestive system
- Introduction
- An overview of the digestive system
- The mouth, pharynx and oesophagus
- The stomach
- The small intestine
- Accessory organs of digestion
- The large intestine
- An overview of nutrition
- Review questions
- Chapter 27 Alterations of digestive function across the life span
- Introduction
- Disorders of the gastrointestinal tract
- Clinical manifestations of gastrointestinal tract alterations
- Disorders of the hepatobiliary system and pancreas
- Review questions
- Chapter 28 The structure and function of the urinary system
- Introduction
- The structure of the kidneys
- The function of the kidneys
- Urine
- Urinary structures
- Micturition
- Review questions
- Chapter 29 Fluids and electrolytes, acids and bases
- Introduction
- Fluid balance
- Electrolyte balance
- Acid–base balance
- Review questions
- Chapter 30 Alterations of renal and urinary tract function across the life span
- Introduction
- Urinary tract obstruction
- Urinary tract infection
- Glomerular disorders
- Chronic kidney disease
- Acute kidney injury
- Tumours
- Review questions
- Part Five Alterations to continuity
- Introduction
- Chapter 31 The structure and function of the reproductive systems
- Introduction
- The structure and function of the male reproductive system
- The structure and function of the female reproductive system
- Puberty in males and females
- Gametogenesis
- Male and female sexual responses
- Conception, gestation and parturition
- Review questions
- Chapter 32 Alterations of the reproductive systems across the life span
- Introduction
- Classification of reproductive system alterations
- Cancer
- Disorders of the female reproductive system
- Disorders of the male reproductive system
- Disorders of the breast
- Fertility
- Assisted reproductive technologies
- Major sexually transmitted infections
- Review questions
- Part Six Contemporary health issues
- Introduction
- Chapter 33 Introduction to contemporary health issues
- Introduction
- Australia and New Zealand: demographics
- Chronic diseases
- Mental health
- Indigenous health
- Contemporary lifestyle
- Obesity
- Health promotion initiatives
- Review questions
- Chapter 34 Stress and chronic disease
- Introduction
- The general adaptation syndrome
- Stressors
- The detection of stress
- Physiological processes of the stress response
- Physiological effects of the stress response
- Benefits of the stress response
- Health alterations with chronic stress
- Modulation of the stress response
- Stress and sleep
- Review questions
- Chapter 35 Obesity
- Introduction
- The progression to overweight and obesity
- Evaluation of body size
- Obesity
- Metabolic syndrome
- Review questions
- Chapter 36 Type 2 diabetes
- Introduction
- Diabetes mellitus
- Understanding the relationship between obesity and diabetes
- Review questions
- Chapter 37 Cancer
- Introduction
- Cancer is a chronic disease
- Cancer characteristics and terminology
- The genetic basis of cancer
- Types of gene mutations in cancer
- Cancer, immunity, inflammation and infection
- Gene–environment interaction
- Diagnosis and evaluation of cancer
- Clinical manifestations of cancer and cancer treatments
- Cancer treatments
- Cancers of greatest significance in Australia and New Zealand
- The role of cancer screening
- Cancer across the life span
- Review questions
- Chapter 38 Genes, genetic diseases and the environment
- Introduction
- Studying genetic disease
- Genetic disorders
- Single gene disorders
- Multifactorial inheritance
- Conditions arising from genetic and environmental factors
- The relative importance of genetic and environmental contributions to disease
- The prevention of disease
- Genetic screening
- Review questions
- Chapter 39 Neurobiology of mental illness
- Introduction
- The epidemiology of mental illness in Australia and New Zealand
- Genetics and mental illness
- Neurotransmitters
- Classification systems
- Anxiety disorders
- Mood disorders
- Schizophrenia
- Substance use
- Eating disorders
- Personality disorders
- Review questions
- Chapter 40 Indigenous health issues in Australia
- Introduction
- The Indigenous Australian population
- Indigenous health
- Conditions affecting the wellbeing of Indigenous Australians
- Common threads — factors contributing to health problems
- Social determinants of Indigenous health
- Closing the Gap
- Review questions
- Chapter 41 Māori health in Aotearoa New Zealand
- Introduction
- The New Zealand Māori population
- Māori health
- Conditions affecting the wellbeing of Māori
- Factors contributing to health problems
- Social determinants of Māori health
- Review questions
- Appendix A Normal reference laboratory values
- Appendix B Prefixes, suffixes and root words commonly used in health sciences
- Glossary
- References
- Image and text credits
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understanding pathophysiology 3rd edition pdf
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